Genoma eldono estas la preciza celata modifo de la nucleótidos sekvenco de la genaro.

En la kazo de CRISPR / Cas9, gvidilon RNA prenas la lokon de DNA liganta proteinon, therefore simplifying the process. CRISPR stands forClustered Regularly Interspaced Short Palindromic Repeats (CRISPR)”.

The CRISPR/Cas9 system is based on a bacterial defense system against foreign DNA (Ekz. Virusoj), whereby an RNA guided nuclease makes highly targeted cuts in the genome.

The CRISPR-Cas9 complex consists of (vidu bildon sube)

  • a Cas9 protein (Cas9 signifas “CRISPR asociitaj)
  • sola gvidisto RNA (sgRNA)

Ligoj: