Jenomu editing ni sahihi walengwa urekebishaji wa mpangilio wa nyukleotidi wa jenomu.
Kwa upande wa CRISPR / Cas9, mwongozo RNA inachukua nafasi ya DNA protini kisheria, therefore simplifying the process. CRISPR stands for “Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)”.
The CRISPR/Cas9 system is based on a bacterial defense system against foreign DNA (e.g. virusi), whereby an RNA guided nuclease makes highly targeted cuts in the genome.
The CRISPR-Cas9 complex consists of (kuona picha hapa chini)
- a Cas9 protein (Cas9 anasimama kwa “CRISPR kuhusishwa)
- single kuongoza RNA (sgRNA)
Viungo:
- https://geneticliteracyproject.org/category/gene-editing/?mc_cid=2335049bf7&mc_eid=0d9495ef74
- Halisi nafasi na muda halisi mienendo ya CRISPR-Cas9 visualized na yenye kasi ya atomiki nguvu hadubini (2017-11)
- Astonishing Video Inaonyesha CRISPR Editing DNA katika Wakati Halisi (2017-11)
- Matumizi ya mfumo wa CRISPR katika mmea genome editing, Ricroch na wenzake 2017
- Mutant Menu
- http://www.arte.tv/guide/en/063945-025-A/gene-editing-in-plants
- Allergenicity tathmini ya Cas9 protini anaona si uwezekano wa kuwa na chakula allergen (2017)
- Vox: mwongozo rahisi CRISPR, moja kubwa ya hadithi sayansi ya 2016
- DNA bure genome uhariri wa ngano – 2016 – 12
- Wheat CRISPR mfupi DNA au RNA kujieleza – 2016 – 04
- Jenomu Editing na CRISPR-Cas9
- Jennifer DOUDNA (UC Berkeley / HHMI): Jenomu Engineering na CRISPR-Cas9
- http://www.nature.com/news/crispr-gene-editing-is-just-the-beginning-1.19510
- http://genomebiology.biomedcentral.com/articles/10.1186/s13059-015-0826-7
- https://www.youtube.com/watch?v = MnYppmstxIs&programu desktop =
- Titanic clash juu patent CRISPR zamu mbaya, http://www.nature.com/news/titanic-clash-over-crispr-patents-turns-ugly-1.20631
- Agricultural R&D ni juu ya hoja, http://www.nature.com/news/agricultural-rd-is-on-the-move-1.20571
