Izpildu sekretārs PRRI ir Dr. Lucia de Souza, a Brazilian national who obtained her Ph.D in plant biochemistry at the Friedriech Miescher Institut in Switzerland. Viņa guvusi pieredzi biotehnoloģiju produktu laišanu tirgū un patērētāju uztveres pētījumu Meksikā un Brazīlijā. Lúcia de Souza has extensive experience in teaching and has been actively involved in biosafety since 1994. No 2005 līdz 2015 she was the vice-president of the Brazilian National Biosafety Association(ANBio), kas ir grupa akadēmisko darbojošos profesionāļu kapacitātes un komunikācijas jomā, bioloģisko drošību un tās saskarnēm ar sabiedrību, regulatoriem un citām ieinteresētajām personām. Kopš 2015 she is affiliated with ISAAA. Lucia de Souza also directs the Switzerland based Cutting Edge Solutions, kas piedāvā konsultācijas par bioloģisko drošību un biotehnoloģija. Lúcia de Souza ir aktīvi iesaistīta PRRI darbībā, jo 2005.
PRRI is an organisation by public researchers for researchers. Over the years PRRI members frequently volunteered to help on an ad-hoc basis the respective Executive Secretaries with secretarial support, such as updating literature on the website, acting as local organisers for meetings in their countries, selecting suitable accommodation during international meetings, uc.
Turklāt, Piet van der Meer provides technical support to PRRI and the PRRI Secretariat . Piet van der Meer is trained as a biologist and a lawyer, un no 1989 līdz 2000 he was in charge of biosafety regulation in the Netherlands during which he was actively involved in many international and EU fora. No 1999 līdz 2002, viņš vadīja projekts "Nacionālās bioloģiskās drošības ietvaru no pirmspievienošanās valstīm Centrālajā un Austrumeiropā", un no 2002 līdz 2004 he served as the programme manager of the UNEP-GEF projects on Implementation of National Biosafety Frameworks. Kopš 2004, Piet van der Meer works as an independent consultant, primarily providing support on biotechnology and biosafety to international organisations and governmental institutes. Turklāt, he teaches since 2006 biotechnology regulation at the University of Ghent (at the Faculty of Sciences and the Faculty of Law), and since 2014 he also teaches this topic at the Free University of Brussels.