edición xenoma é a modificación dirixida precisa da secuencia de nucleótidos do xenoma.

No caso de CRISPR / cas9, un ARN guía asume o lugar dunha proteína de conexión de ADN, therefore simplifying the process. CRISPR stands forClustered Regularly Interspaced Short Palindromic Repeats (CRISPR)”.

The CRISPR/Cas9 system is based on a bacterial defense system against foreign DNA (e.g. virus), whereby an RNA guided nuclease makes highly targeted cuts in the genome.

The CRISPR-Cas9 complex consists of (vexa a imaxe de abaixo)

  • a Cas9 protein (Cas9 significa “CRISPR asociado)
  • nun ARN de guía (sgRNA)

Ligazóns: