koreksyon genomic se egzak modifikasyon an vize nan sekans lan nukleotid nan genomic a.
Nan ka a nan CRISPR / Cas9, yon RNA gid pran plas la nan yon obligatwa pwoteyin ADN, kidonk senplifye pwosesis la. CRISPR la vle di “Gwoup Repetisyon palindromik ki entèpase regilyèman (CRISPR)”.
Sistèm CRISPR/Cas9 la baze sou yon sistèm defans bakteri kont ADN etranje (e.g. viris), kote yon nukleaz RNA gide fè koupe trè vize nan genòm nan.
Konplèks CRISPR-Cas9 konsiste de (wè foto ki anba a)
- yon pwoteyin Cas9 (Cas9 kanpe pou “CRISPR asosye)
- yon sèl gid RNA (sgRNA)
Lyen:
- https://geneticliteracyproject.org/category/gene-editing/?mc_cid=2335049bf7&mc_eid=0d9495ef74
- Imobilye-espas ak an tan reyèl dinamik nan CRISPR-Cas9 vizualiz pa segondè-vitès mikwoskospi atomik fòs (2017-11)
- Yon Videyo Etonan Montre CRISPR Korije ADN nan Real Time (2017-11)
- Sèvi ak nan sistèm CRISPR nan plant koreksyon genomic, Ricroch et al 2017
- tòti Menu
- http://www.arte.tv/guide/en/063945-025-A/gene-editing-in-plants
- evalyasyon alèrjèn nan Cas9 pwoteyin jwenn li se pa chans yo dwe yon allergen manje (2017)
- Vox: Yon gid senp yo CRISPR, youn nan istwa yo syans pi gwo nan 2016
- ADN gratis genomic koreksyon ki gen ble – 2016 – 12
- Ble CRISPR pasajè ADN oswa RNA ekspresyon – 2016 – 04
- Genomic Korije ak CRISPR-Cas9
- Jennifer DOUDNA (UC Berkeley / HHMI): Genomic Sivil ak CRISPR-Cas9
- http://www.nature.com/news/crispr-gene-editing-is-just-the-beginning-1.19510
- http://genomebiology.biomedcentral.com/articles/10.1186/s13059-015-0826-7
- https://www.youtube.com/watch?v = MnYppmstxIs&app = Desktop
- Titanic konfli sou rive CRISPR vire lèd, http://www.nature.com/news/titanic-clash-over-crispr-patents-turns-ugly-1.20631
- Agrikilti R&D se sou mouvman an, http://www.nature.com/news/agricultural-rd-is-on-the-move-1.20571
