Den verkställande sekreterare PRRI är Dr. Lucia de Souza, a Brazilian national who obtained her Ph.D in plant biochemistry at the Friedriech Miescher Institut in Switzerland. Hon erfarenhet inom bioteknik produktlansering och konsumenternas uppfattning forskning i Mexiko och i Brasilien. Lúcia de Souza has extensive experience in teaching and has been actively involved in biosafety since 1994. Från 2005 till 2015 she was the vice-president of the Brazilian National Biosafety Association(ANBio), vilket är en grupp av akademiska personal verksamma inom kapacitetsuppbyggnad och kommunikation inom området biosäkerhet och dess gränssnitt mot samhället, tillsynsmyndigheter och andra intressenter. Eftersom 2015 she is affiliated with ISAAA. Lucia de Souza also directs the Switzerland based Cutting Edge Solutions, som erbjuder konsulttjänster inom biosäkerhet och bioteknik. Lucia de Souza har varit aktivt involverad i PRRI s verksamhet sedan 2005.
PRRI is an organisation by public researchers for researchers. Over the years PRRI members frequently volunteered to help on an ad-hoc basis the respective Executive Secretaries with secretarial support, such as updating literature on the website, acting as local organisers for meetings in their countries, selecting suitable accommodation during international meetings, etc..
Dessutom, Piet van der Meer provides technical support to PRRI and the PRRI Secretariat . Piet van der Meer is trained as a biologist and a lawyer, och från 1989 till 2000 he was in charge of biosafety regulation in the Netherlands during which he was actively involved in many international and EU fora. Från 1999 till 2002, Han lyckades projektet "Implementering av nationella biosäkerhet ramarna för kandidatländerna i Central-och Östeuropa", och från 2002 till 2004 he served as the programme manager of the UNEP-GEF projects on Implementation of National Biosafety Frameworks. Eftersom 2004, Piet van der Meer works as an independent consultant, primarily providing support on biotechnology and biosafety to international organisations and governmental institutes. Dessutom, he teaches since 2006 biotechnology regulation at the University of Ghent (at the Faculty of Sciences and the Faculty of Law), and since 2014 he also teaches this topic at the Free University of Brussels.