Genome editing yog tus leej ntxiv yog hloov tus lawv liag nucleotide lub genome.
Dhau lub xyoo caum programmable DNA binding proteins muaj tau tsim uas yuav qhia tau ib nuclease txiav ntawm tej targeted taw tes rau hauv lub genome.
Lub Transcription activator zoo li nyhuv (TALEAS) Txheej txheem siv tej proteins uas bind rau DNA hauv ib
theem-txoj kev, Tas cov fused nuclease txiav raws li ib tug “DNA scissor’ nyob ntawd qhov chaw ntawd.
Lub kaw lus no consists ntawm:
- ib "TAL-effector " domain (recognising ib theem ntawm puag khub ib los ntawm ib tug nyob rau hauv cov DNA sequence)
- Ib nuclease uas to thiab ob-tso tseg DNA.
